I assume that by AMR you mean adaptive mesh refinement. Support for adaptive meshes is not yet available in preCICE, but it is in our roadmap. (cc @fsimonis)
What does “without success” mean?
One participant can carry multiple meshes, but not multiple copies of preCICE itself (multiple interfaces). I am not sure if that’s what you mean and something you need, as it has not really been needed so far. It is, however, also on our roadmap.